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How do you incorporate TTFields into your clinical practice?

Do you routinely recommend TTF in the adjuvant setting for patients with glioblastoma?
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When do you discuss TTFields with patients who will be undergoing chemoradiation for resected glioblastoma?

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5 Answers
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Radiation Oncology · Duke University School of Medicine
Answered on

I recommend TTFields to all patients with newly diagnosed glioblastoma. I generally approach this during the second or third week of radiation treatment. I present TTFields as part of standard treatment for glioblastoma, similar to the discussion of adjuvant temozolomide.

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Radiation Oncology · Florida International University
Answered on · Updated on

Based on the long-term phase III randomized trial data on the use of TTF, which demonstrate a categorical survival benefit, we use a data-driven approach for all of our newly-diagnosed GBM patients. We recognize that considerable angst and controversy still exists regarding these data, but there are...

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Radiation Oncology · McGill University
Answered on

In our department, we utilize a multi-disciplinary approach. Surgeons, medical oncologists and radiation oncologists all play a role in recommending TTF in the adjuvant setting for newly diagnosed glioblastoma. Medical oncology nurses meet with the patients to provide chemotherapy education. During ...

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Radiation Oncology · Columbia University Irving Medical Center
Answered on

Since the publication of EF-14 in 2017, I would say in my practice a fair amount of patients have already read about TTF in the adjuvant setting for glioblastoma. Generally, I’d discuss the data and current national guidelines regarding TTF such as NCCN. For patients who are getting the standard six...

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Radiation Oncology · Banner M.D. Anderson Cancer Center
Answered on

While we don't often address cost, I do think that should be discussed in this forum. This will only become more of an issue as we move towards alternative payment models which eventually could combine all oncology care.

The therapy costs about $20K per month. The Incremental Cost Effectiveness rati...

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