Topics:
Pediatric Oncology • Rheumatology • Hematology • Pediatric Hematology • Antiphospholipid Syndrome • Benign Hematology
How do you interpret elevations in antiphospholipid antibodies that are lower than Sapporo criteria?
(e.g. beta 2 glycoprotein IgM > 20 but <40)
Answer from: at Academic Institution
I would refer to the following article that provides the most up-to-date definitions (including the definitions for low-level antibodies) and risk stratification tools including APL-S and GAPSS that are developed for people with autoimmune conditions. The article also discusses the levels of evidenc...
Sign in or Register to read more
Answer from: at Academic Institution
I would seriously consider positive aPL test results in the context of other factors, such as clinical evidence for thrombosis or positive ANA.