How do you manage adjuvant endocrine therapy for microinvasive HR-positive disease measuring >=1mm in extension?  

I manage unifocal T1mi disease similar to ER+ DCIS by discussing 5 years of endocrine therapy. The treatment is not so much to avert metastatic recurrence rather it is to lower the risk of a subsequent breast cancer in any remaining natural breast tissue. If they had bilateral mastectomies then I do...