NCI-CCC Breast Tumor Board Question   

Questions discussed in this category



Pre-menopausal women make progesterone and their menses are typically lighter on tamoxifen because it's a mild endometrial ER stimulant blocking their...

Would you obtain baseline PFT on all patients or only selected high risk patients? Would you repeat PFTs regularly or only if clinically symptomatic?&...

Patient had a clinical T2N0 cancer at diagnosis, completed 6 cycles TCHP, and had 0.2mm residual disease with 80% cellularity, negative sentinel node.

For a patient with high risk disease and a severe enough reaction that additional taxane-based therapy is contraindicated, do you consider alternate c...

She had had 4 prior biopsies. Would the fact that she received 2 months of neoadjuvant tamoxifen due to COVID change your approach?

Is there any evidence for sacituzumab govitecan (IMMU-132) in this situation with progressive systemic disease after prior anthracycline and taxane?

This patient underwent mastectomy and ALND (10/28 positive lymph nodes). Immediately following axillary LN dissection (and prior to radiation) imaging...

For patients with low risk, early stage, hormone receptor positive, HER2 negative breast cancer who initiated endocrine therapy in order to delay thei...

Would you offer this patient chemotherapy? What are your thoughts about OFS plus AI and avoiding chemotherapy?

Following the dosage guidelines based on absolute neutrophil count may cause the patient to end up receiving lower doses.

(For instance, TCX4 instead of AC->T for smaller tumors?)Does this affect your decision about treating with neoadjuvant versus adjuvant chemotherap...


Papers discussed in this category


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003-03-15

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-03-10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-08-10

The New England journal of medicine, 2019-06-20

The Lancet. Oncology, 2017-12

N. Engl. J. Med.,

Breast, 2013 Dec 22

Breast, 2015 Oct 09

Lancet Oncol., 2020 Feb 14

International journal of radiation oncology, biology, physics, 2005-07-15

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-07-01

The New England journal of medicine, 2018-07-12

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-08-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-04-20

J. Clin. Oncol., 2019 Oct 16

Breast cancer research and treatment, 2014-11

The Lancet. Oncology, 2016-03

N Engl J Med, 2018 Oct 20

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-04-01

The New England journal of medicine, 2019-02-14

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-07-20

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-04-10

Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01

Journal of the National Cancer Institute, 2005-11-16

Cancer, 2020 Jun 10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-08-10

The New England journal of medicine, 2018-07-12

Journal of the National Cancer Institute, 1997-11-19

Journal of surgical oncology, 2017-06

The New England journal of medicine, 2016-08-25

Annals of oncology : official journal of the European Society for Medical Oncology, 2000-08

Obstet Gynecol,

JAMA,

Cancer Prev Res (Phila), 2019 Aug 16