Questions discussed in this category
In a patient who is not a surgical candidate, do you offer concurrent carbo/taxol rather than 5FU/oxaliplatin?
Would you use FOLFIRINOX as in Prodige 23 or FOLFOX as in RAPIDO?
For a patient with high risk disease and a severe enough reaction that additional taxane-based therapy is contraindicated, do you consider alternate c...
Is there an advantage to early diagnosis and intervention versus observation until the nodules are amenable to percutaneous biopsy?
I am considering every 6 week pembrolizumab dosing in patients >70 years old in whom I want to reduce clinic visits for, especially in the context ...
Should staging and treatment decisions be made based on imaging alone?
If so, how long is too long to wait?
How, if any, do you utilize genomic testing to guide systemic therapy?
Ampullary carcinoma is not in the NCCN guidelines. Please address not only the role for therapy but the optimal regimen (i.e. Gem based, vs mFOLFIRINO...
If so, what is your approach to sequencing and timing of targeted therapy and local therapy?
If so do you favor repeat tumor biopsy or cfDNA?
What if the patient has thymoma-associated myasthenia gravis?
Is there any role for denosumab? How do you counsel patients regarding the benefit of bisphosphonates on breast cancer outcomes?
How does the timing of recurrence play into your decision?
When would you favor delivering local therapy (e.g. SBRT) prior to systemic therapy?
Would you treat this as a locally advanced breast cancer and offer surgery, radiation, and systemic therapy? Does your management change depending on ...
These patients have been largely excluded from these trials. What if the infection is well controlled?
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Papers discussed in this category
Breast Cancer, 2012 Apr 25
Annals of surgical oncology, 2018-10
Lancet Oncol., 2015 Sep 09
BMJ, 2016 Sep 30
The New England journal of medicine, 2016-08-25
The New England journal of medicine, 2018-07-12
Journal of the National Cancer Institute, 2017-02
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-04-10
The Lancet. Oncology, 2012-07
Annu. Rev. Med., 2015 Aug 28
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-06-20
J. Clin. Oncol., 2018 Jun 15
The Lancet. Oncology, 2015-02
J. Clin. Oncol., 2017 Dec 14
The New England journal of medicine, 2018-12-13
JAMA, 2012 Jul 11
Radiation oncology (London, England), 2011-09-28
JAMA surgery, 2019-05-29
Clin Transl Oncol, 2018 Mar 28
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003-03-15
N. Engl. J. Med.,
Breast, 2013 Dec 22
Breast, 2015 Oct 09
Cancer, 2011-11-01
Case reports in oncology, 2017
BMC Cancer, 2015 Oct 15
Lancet Oncol., 2015-09-01
J. Thorac. Cardiovasc. Surg.,
Cancer, 2015 Jan 06
Eur J Cardiothorac Surg,