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Questions discussed in this category



For a patient with high risk disease and a severe enough reaction that additional taxane-based therapy is contraindicated, do you consider alternate c...

I am considering every 6 week pembrolizumab dosing in patients >70 years old in whom I want to reduce clinic visits for, especially in the context ...

Should staging and treatment decisions be made based on imaging alone?

Ampullary carcinoma is not in the NCCN guidelines. Please address not only the role for therapy but the optimal regimen (i.e. Gem based, vs mFOLFIRINO...

Is there any role for denosumab? How do you counsel patients regarding the benefit of bisphosphonates on breast cancer outcomes?

When would you favor delivering local therapy (e.g. SBRT) prior to systemic therapy?

Would you treat this as a locally advanced breast cancer and offer surgery, radiation, and systemic therapy? Does your management change depending on ...

These patients have been largely excluded from these trials.  What if the infection is well controlled?


Papers discussed in this category


Breast Cancer, 2012 Apr 25

Annals of surgical oncology, 2018-10

Lancet Oncol., 2015 Sep 09

BMJ, 2016 Sep 30

The New England journal of medicine, 2016-08-25

The New England journal of medicine, 2018-07-12

Journal of the National Cancer Institute, 2017-02

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-04-10

The Lancet. Oncology, 2012-07

Annu. Rev. Med., 2015 Aug 28

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-06-20

J. Clin. Oncol., 2018 Jun 15

The Lancet. Oncology, 2015-02

J. Clin. Oncol., 2017 Dec 14

The New England journal of medicine, 2018-12-13

JAMA, 2012 Jul 11

Radiation oncology (London, England), 2011-09-28

JAMA surgery, 2019-05-29

Clin Transl Oncol, 2018 Mar 28

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003-03-15

N. Engl. J. Med.,

Breast, 2013 Dec 22

Breast, 2015 Oct 09

Cancer, 2011-11-01

Case reports in oncology, 2017

BMC Cancer, 2015 Oct 15

J. Thorac. Cardiovasc. Surg.,

Cancer, 2015 Jan 06

Eur J Cardiothorac Surg,