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How do you manage endocrine therapy for a perimenopausal woman with ER+ breast CA?

The woman was on on a GnRH agonist + AI due to her premenopausal status at diagnosis and now wants to know if she continues to need the GnRH agonist.
1 Answer
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Medical Oncology · Warren Alpert Medical School of Brown University
Answered on

In lower risk patients to whom I would not routinely give chemotherapy - stage I-IIA, with a low or low-intermediate risk Oncotype score - I start tamoxifen and switch to an aromatase inhibitor (except in very low risk patients in whom the benefit of switching would be negligible) when they are clin...

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