How do you time same-day chemotherapy and radiation for patients undergoing concurrent chemoRT?

A great question. It is similar to recipes for pasta sauce - with rare exception no matter how you make it, it's usually good.

There are retrospective data which suggest that capecitabine is most effective one hour prior to RT. That is the ideal sequence. However, since it is prescribed q12 hours it...

When possible we try to deliver chemo prior to RT. Probably makes more sense for oral drugs given daily than IV drugs weekly (or less often). We do have a hard and fast rule that CRT starts on M/T/W but not Thursday or Friday. In head and neck cancers, if the patient gets RT first and chemo starts l...

I don’t think that the precise timing matters.