How do you treat duodenal adenocarcinoma when using primary chemoradiation therapy?
What dose/fractionation do you use and what elective nodal areas do you cover? What studies do you order to aide in treatment planning (PET/CT? MRI?) when the lesion is not seen well on CT?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on · Updated on
We treat them the same as rectal cancer. Induction FOLFOX, followed by 50.4Gy in 28 with concurrent capecitabine. The responsiveness to these therapies is about the same, including cCR rate of 30% and ultimate LC without surgery 20%. There is no role for PET, we use CT CAP with contrast. The tumor +...
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