How do you use baby tam, low dose tamoxifen, in your practice?
1 Answer
Mednet Member
Medical Oncology · Indiana University School of Medicine
Answered on
At SABCS 2022, we heard additional follow up results from Dr. DeCensi for TAM-01 (previous publication), which randomized patients with DCIS, LCIS, or atypia to low dose tamoxifen (5 mg daily) or placebo for 3 years. Similar to the prior full dose tamoxifen prevention trials, this resulted in about a 40% reduction in breast cancer or DCIS events but with very little toxicity. We will not see a trial of 5 mg versus 20 mg as this would result in too few events and need to be a very large trial. Th...
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