How does the presence of CABG affect your radiotherapy approach for definitive management of locally advanced NSCLC with mediastinal involvement?

This is a great question. The short answer is we don’t exactly know – but the longer answer would be that while CABG graft dosimetry hasn’t been explicitly defined, we can make a few reasonable extrapolations and assumptions. We know that patients with +CAD are at very high risk of cardiac events, a...

I learned a while ago from @Dr. First Last to not push the intermediate doses around based on hypothesized limits to make ourselves feel better about a plan. We simply need to think about the normal anatomy, organ function, and its current physiological state to counsel our patients about the risk o...