How long do you treat uncomplicated gram-negative rod bacteremia in solid organ transplant recipients?
1 Answer
Mednet MemberInvited Expert
Infectious Disease · Johns Hopkins University
Answered on · Updated on
My approach to the duration of therapy for GNR bacteremia in SOT patients depends on the source of the bacteremia, the available antibiotics, the patient's net state of immunosuppression, and the organism. There are situations where 7 days of therapy are adequate (One example: E.coli urosepsis in a female liver transplant recipient 7 years from transplant with no recent rejection episodes on low-dose prednisone and CNI). There are other instances where I prefer a longer course of treatment closer to 14 days (One example: 2nd recurrence of pseudomonas bacteremia in a kidney transplant recipient within 1 year of transplant who also recently had CMV viremia).
Join for free or sign in to see the full answer