Topics:
Breast Cancer • Medical Oncology
How would you approach a patient with early stage breast cancer on adjuvant docetaxel that developed lacrimal duct obstruction after 2 cycles?
Status post nasolacrimal stent with improvement. Would you re-challenge or permanently discontinue docetaxel?
Answer from: Medical Oncologist at Academic Institution
If a patient has already developed one duct requiring stenting I would probably discontinue the docetaxel and substitute paclitaxel or nab-paclitaxel, which do not appear to have similar ocular toxicities. This is uncommon with q3wk administration of docetaxel but is drug-specific and your pat...
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