How would you approach patients with primary cardiac sarcomas for adjuvant systemic treatment?

Majority of these primary cardiac sarcomas tend to be angiosarcomas or UPS-variants. They inherently have a poor prognosis with high risk of metastases and death. Adjuvant XRT is generally difficult in this location. These also generally affect young individuals with o/w good PS/organ function. So w...

I agree with Dr. @Dr. First Last. I would also test the sarcoma for genomics.