How would you approach the treatment of isolated lesions within the spleen for a patient with metastatic small cell lung cancer and well-controlled disease elsewhere after chemotherapy?
Would you offer SABR in the setting of only two lesions? How would your recommendation change if this was NSCLC?
Answer from: Radiation Oncologist at Academic Institution
While it may be tempting to consider SBRT for this oligoresidual case, there really isn’t a lot of data to support such a strategy.
Extensive stage small cell has a poor prognosis, and the roles of pci and consolidative thoracic RT have camps of believers and non-believers. RTOG 0937 wa...
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Answer from: Radiation Oncologist at Academic Institution
I agree with @Alexander V. Louie above on the answer for SCLC. This was evaluated and answered as being not beneficial to OS in RTOG 0937. In fact, numerically, the 1-year survival was worse in the consolidative RT arm. I do not offer consolidative RT for ES-SCLC outside of TRT.To answer the se...