How would you approach the treatment of isolated lesions within the spleen for a patient with metastatic small cell lung cancer and well-controlled disease elsewhere after chemotherapy?

While it may be tempting to consider SBRT for this oligoresidual case, there really isn’t a lot of data to support such a strategy.

Extensive stage small cell has a poor prognosis, and the roles of pci and consolidative thoracic RT have camps of believers and non-believers. RTOG 0937 was a consolid...

I agree with @Dr. First Last above on the answer for SCLC. This was evaluated and answered as being not beneficial to OS in RTOG 0937. In fact, numerically, the 1-year survival was worse in the consolidative RT arm. I do not offer consolidative RT for ES-SCLC outside of TRT.

To answer the second port...