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How would you approach treatment of residual melanoma in situ of the perianal skin?

Would you recommend adjuvant radiotherapy for a patient with positive margins for in situ disease with negative margins for invasive disease? If so, what technique and dose-fractionation would you consider?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan Kettering Cancer Center
Answered on

It sounds like this is a case of mucosal melanoma of the anal canal, with extension on to the perianal skin? Alternatively, this could be a case of true cutaneous melanoma on perianal skin. Further investigations might be helpful to clarify.

In either case, this is an unusual situation in this anatom...

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