How would you counsel a patient with HR+, HER2- breast cancer with an OncotypeDx ROR score of 0 who is refusing endocrine therapy?

This is often a challenging case to discuss with patients. Although we know that this patient's likelihood of distant recurrence is very low if she takes 5 years of adjuvant endocrine therapy, we don't actually know what her risk of recurrence is with no systemic therapy. Presumably, those with very...

An occasional scenario in a busy breast practice. From personal experience, I have seen a few with a score of zero and in that case, it is important to correlate with pathologic findings, how the cancer was discovered, and then balance treatment options against low risk of recurrence. These would be...