How would you manage a cN0 penile cancer with a moderate risk of nodal metastasis?

Pathologic nodal stage is such a strong prognostic factor that patients with moderate or high risk of nodal involvement, even if cN0, should have surgical nodal staging. This includes those patients with MD and PD tumours, and T1b or higher.

PET-CT cannot show microscopic involvement.

If the patien...