How would you manage a patient who developed stage III melanoma while receiving cemiplimab (cycle 10) for locally advanced cutaneous squamous cell carcinoma?

That depends on whether you want to manage the stage III melanoma in the adjuvant vs neoadjuvant setting. If adjuvant, can likely continue cemiplimab (off-label for melanoma) as it has the same MoA as other anti-PD-1 ICI. If intending to manage stage III melanoma in neoadjuvant setting, consider swi...

Is this clinical stage 3 or stage 3 melanoma with microscopic metastasis to the lymph node? If clinical stage 3 melanoma, then perhaps, I think the best route to go would be to treat with ipi-nivo combination. I would prefer to use ipi-3 and nivo-1 based on the S1616 data rather than ipi-1 and nivo-...