Topics:
Rheumatology • Thrombosis • Antiphospholipid Syndrome • Systemic lupus erythematosus • Anticoagulation
How would you manage a patient with SLE that has a remote history of positive anti-phospholipid antibodies with a current DVT and now completely negative APLs?
Would you still plan for lifelong anticoagulation in this scenario?
Answer from: at Academic Institution
Assuming the reliability of the lab report indicating negative antiphospholipid antibodies (APL) and the absence of any other manifestations as per the latest APLS guidelines, I generally would not factor a distant history of APL positivity when determining the management of this patient.While the f...
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