How would you manage adjuvant treatment of a premenopausal woman with HER2 positive, ER/PR negative multifocal micro-invasive node-negative breast cancer?

Topics: Breast Cancer • Medical Oncology • NCI-CCC Tumor Board Question • Her2+ • University of Iowa • NCI-CCC Breast Tumor Board Question • Breast Cancer, Non-metastatic

Largest invasive focus is 0.4mm

Answer from: Medical Oncologist at Academic Institution

I would not typically recommend any adjuvant chemotherapy + HER2 directed therapy for a T1mi N0 breast cancer. For T1a, the risk of distant recurrence also is likely low based on observational series, so observation is also reasonable. However, as per NCCN guidelines, it is also appropriate to consi...

Comments

Medical Oncologist at UW Madison
Agree! There is also some discussion of similar cl...

Related Questions