How would you treat a patient with locally advanced HR+ breast cancer with contralateral axillary lymph node involvement?
No primary identified in the contralateral breast. No distant metastasis identified.
Answer from: Medical Oncologist at Academic Institution
Locally advanced breast cancers, particularly those with substantial nodal burden, can cause aberrant lymphatic drainage patterns, including to the contralateral side. For this reason, in a patient with LABC and contralateral nodal involvement, we look for a contralateral primary and distant disease...
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