How would you treat a patient with recurrent brain mets from small cell lung cancer who has already received previous whole brain radiotherapy (30 Gy in 10fx)?

We tend to treat these patients with stereotactic radiosurgery and will treat up to 10 lesions given prior whole brain radiation therapy. We know from studies, however, that despite radiosurgery, they tend to recur elsewhere in the brain and that the need for future SRS salvage is higher than with o...

Agree with Dr Chao. This answer depends on a number of factors, extracranial disease burden and performance status in particular. At UAB, we are willing to treat amuchhigher number of lesions than 10 (we have treated up to 27 breast cancer metson our Edge), but in SCLC patients with >10 mets, the pa...