How would you treat a patient with recurrent brain mets from small cell lung cancer who has already received previous whole brain radiotherapy (30 Gy in 10fx)?

Topics: Radiation Oncology • Neuro-Oncology • Thoracic Malignancies

Is there a size or number of metastasis cut-off where you would consider SRS vs. WBRT?

Answer from: Radiation Oncologist at Academic Institution

We tend to treat these patients with stereotactic radiosurgery and will treat up to 10 lesions given prior whole brain radiation therapy. We know from studies, however, that despite radiosurgery, they tend to recur elsewhere in the brain and that the need for future SRS salvage is higher than ...

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Radiation Oncologist at Medical Center East Cancer Center
What dose fractionation schedule is used?

Radiation Oncologist at Cleveland Clinic
We do standard RTOG dosing so 2 cm or less, 24 Gy;...

Answer from: Radiation Oncologist at Academic Institution

Agree with Dr Chao. This answer depends on a number of factors, extracranial disease burden and performance status in particular. At UAB, we are willing to treat amuchhigher number of lesions than 10 (we have treated up to 27 breast cancer metson our Edge), but in SCLC patients with >10 mets, the...

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