How would you treat a patient with small cell ca of the appendix with no evidence of distant mets?

Small cell carcinomas of the appendix are exceedingly rare and one has to question if that truly is the origin of the tumor. High-grade neuroendocrine carcinoma, including both small-cell and large-cell, is much more commonly seen in the large bowel, often in the cecum.

There are extremely limited da...

I agree. Small cell or high grade neuroendocrine carcinoma has a high propensity of metastases, adjuvant platinum based chemotherapy to improve survival.