How would you treat an endometrial cancer with pelvic sidewall nodes, patient s/p TAH/BSO but nodes were fixed and unresectable?

We would treat with IMRT and IGRT with concurrent cisplatinum based chemotherapy, with SIB boost dose to involved nodes (dose based on size and proximity of critical organs) followed by adjuvant chemo.

As long as the patient is in good performance status and has no distant Mets, I agree with an aggressive approach, which would include chemotherapy and radiation; however, the sequencing of each is variable.

We would typically do the sandwich approach: 3 cycles of chemo, then radiation (SIB boost th...