If a patient achieves excellent clinical/radiographic response to neoadjuvant THP, would you omit AC and proceed with surgery?
Would it make a difference in terms of OS if the patient received AC?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · University of Texas MD Anderson Cancer Center
Answered on
If a patient has had only 4 cycles of THP (similar to the NeoSphere Trial preoperative component), then the standard of care is still to proceed with anthracycline-based therapy as we do not yet know if the favorable outcome associated with pCR applies to abbreviated therapy. However, for a patient ...
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