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Topics:
Infectious Disease
•
Tuberculosis
•
Latent Tuberculosis
If a patient does not tolerate completion of a course of LTBI treatment with either 6-9INH or 3HP, is it reasonable to complete a subsequent partial course of rifampin alone, or does the rifampin treatment course need to be re-started?
Related Questions
How do you approach ongoing screening for TB in patients with a history of treated latent TB, but who have ongoing use of DMARDs and/or biologics given Quantiferon testing and PPD can remain positive?
What is the preferred four-drug regimen for initial treatment of pan-susceptible tuberculous meningitis, given the need to achieve optimal CNS penetration?
Does your institution have formal policies or work flows to reduce unnecessary IGRAs ordered for patients on biologics?
When is drug-level monitoring helpful in the treatment of pan-susceptible tuberculosis on a standard four-drug therapy regimen?
What is your approach to the use of steroids in treatment of CNS tuberculosis?
Do you have a preference between Quantiferon Gold and T-spot TB for screening in patients starting immunosuppressive agents?
For how long do you recommend treatment for latent tuberculosis prior to initiation of anti-TNF therapy?
How do you approach a positive Quantiferon/PPD test result in a patient for whom testing is sent without a clinical indication and who does not have a risk factor for TB exposure nor TB reactivation?
How do you approach treatment of tuberculous scleritis in pregnancy?
How do you approach a patient who has anterior uveitis and is referred for evaluation of ocular TB with a positive Quantiferon gold (as part of their workup) in countries with low TB incidence?