If a patient with low metastatic burden has bulky retroperitoneal adenopathy without osseous metastasis, would you recommend prostatic radiation?

Topics: Radiation Oncology • Genitourinary Cancers

Given CHAARTED and STAMPEDE, what would you recommend? Would lymph node vs osseous mets change your recommendation given the trial did allow patients with metastatic adenopathy?

Answer from: Radiation Oncologist at Academic Institution

We could debate whether "bulky" retroperitoneal adenopathy is a truly low volume metastatic disease, but technically it would fit the definition used in the STAMPEDE Trial. In addition, patients presenting with nodal metastatic disease may have a more indolent course than those presenting de novo wi...

Comments

Radiation Oncologist at Washington University School of Medicine
I agree with @Mitchell S. Anscher's thoughtful com...

Radiation Oncologist at Beth Israel Deaconess Medical Center/Harvard Medical School
Agree. We all look to the Stampede trial to suppor...

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