Mednet Logo

In a patient diagnosed with Multiple Myeloma, is there a role for 24-hour UPEP prior to treatment?

Does measuring serum free-light chains make a 24-hour UPEP unnecessary?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Hematology · USC Keck School of Medicine
Answered on

I’d do a random UPEP first. If no light chains or renal dysfunction, I would not do 24-hour test. If light chains present with renal dysfunction, or significant protein on UA (albumin), I may do 24-hour UPEP and protein quantitation to distinguish myeloma kidney from light chains vs nephrotic syndro...

Join for free or sign in to see the full answer