In a patient diagnosed with Multiple Myeloma, is there a role for 24-hour UPEP prior to treatment?
Does measuring serum free-light chains make a 24-hour UPEP unnecessary?
Answer from: at Academic Institution
I’d do a random UPEP first. If no light chains or renal dysfunction, I would not do 24-hour test. If light chains present with renal dysfunction, or significant protein on UA (albumin), I may do 24-hour UPEP and protein quantitation to distinguish myeloma kidney from light chains vs nephrotic ...
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