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In the treatment of osteoarthritis with low-dose radiation therapy is there data to support the claim that LDRT does not limit or preclude later orthopedic surgery?

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Radiation Oncology · Baylor Scott & White Health

At LDRT doses, the biological effects are anti-inflammatory and immunomodulatory rather than cytotoxic or fibrogenic, and there is no evidence of vascular injury, impaired cellular proliferation, or tissue destruction. Animal models and cellular studies provide robust evidence that LDRT at OA releva...

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Radiation Oncology · Yale Cancer Center At Smilow Cancer Hospital

Completely agree with Dr. @Dr. First Last above. From a clinical and theoretical perspective, as radiation oncologists, we would all readily agree that there is no reason to be concerned about the impact of 3-6 Gy on wound healing or surgical complications.

However, effectively communicating this re...

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