In what scenarios do you consider omitting adjuvant endocrine therapy after lumpectomy for DCIS?
How strongly would you recommend it for a grade 1, < 1 cm DCIS?
Answer from: Medical Oncologist at Community Practice
NSABP 24, 35 Trials. Adjuvant hormone therapy prolongs DFS.
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Answer from: Medical Oncologist at Community Practice
I generally do recommend hormonal therapy for DCIS. Of course, scenarios where that does not apply at those with ER/PR- DCIS or bilateral mastectomies. In addition, the recommendation in patients with DCIS s/p unilateral mastectomy is weaker and only protects against risk in the opposite breast.
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