Is it reasonable to treat with RT alone for limited stage SCLC if unable to receive chemotherapy?

Yes, I think this is reasonable, though obviously expectations should be tempered, as SCLC is essentially a systemic disease and as such, RT alone should be viewed as palliative treatment or aimed at preventing imminent morbidity from local progression. I would consider a hypofractionated regimen su...

Since standard of care is BID treatment (45Gy in 30 fractions), that may be a reasonable option. And a recent abstract suggests a benefit with escalating BID to 60Gy (in 40 fractions), And therefore it would be reasonable to go to this higher dose given that the patient will not be receiving chemo. ...