Is it safe to use doses of 3Gy in a BID treatment for palliative urgent cases?
For example, if a patient had severe lung obstruction or hemoptysis from a tumor would it be okay to treat with 3Gy per fraction BID? Or, if a patient had persistent vaginal and/or bladder bleeding?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · University of Washington
Answered on
This combination of a "hypofractionationated" 3 Gy dose per fraction with a "hyperfractionated" BID schedule has been described in the setting of "quad shot" radiation- most typically associated with head and neck cancers. The goal is to provide robust palliation within a short time frame. The "quad...
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Mednet Member
Radiation Oncology · Northeast Alabama Regional Medical Center
Answered on
Off the cuff re: lung cancer palliation I'd say "yes" it's safe to give 3 gray twice in one day. Because I know it's safe to give 8.5 Gy in one day as part of a 17 Gy palliative regimen (http://ascopubs.org/doi/full/10.1200/jco.2004.06.123). And I have done this rather often. And I have seen these "...
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