Is it safe to use radioactive iodine therapy for patients with differentiated thyroid cancer and brain metastases?

Not all brain metastases from thyroid cancer accumulate radioactive iodine. It is not unsafe to use radioactive iodine in the presence of brain metastases, whether they have been treated with whole brain RT or SRS/SRT. If the brain metastases pick up radioactive iodine, there could be increased peri...

Depending on the situation giving radioactive iodine may be appropriate. I would consider factors including the extracranial disease burden and patient performance status. With regard to prior brain radiotherapy, whether that being whole brain radiotherapy or stereotactic radio surgery, this also de...

Yes, it is safe to use radioactive iodine in thyroid cancer patients with brain metastases. It does not matter whether the brain metastases have been treated with SRS or WBRT.

Paul Sperduto