Is SRS or 3-5 fraction SRT appropriate for cystic brain metastases?

Optimal management of large cystic metastatic brain lesions remains an area of high controversy and debate. One approach would be to aspirate the cyst followed by radiosurgery. Pan and colleagues¹ reported that tumors with a large cystic component (>10 ml) did not appear to be effectively controlled...

The differing views of the cystic metastasis have been discussed. UCSF published on worse control with cystic lesions and I swear this is brought up at almost every stereotactic conference. To my knowledge, this has not been shown in any other retrospective reviews (including in subsequent updated a...