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Is there a clinically significant increased risk of venous thromboembolism with the use of fulvestrant for metastatic HR+ breast cancer?

In a patient with a history of VTE (now off anticoagulants), is it safe to administer fulvestrant?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Icahn School of Medicine at Mount Sinai
Answered on

The reason for VTE? Post-operative, trauma, hypercoagulability due to having cancer or its treatment, hereditary hypercoagulability, or idiopathic? I am going to assume that the VTE was self-limited and treated with a course of anticoagulation. Does fulvestrant cause VTE? Ideally, a randomized place...

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