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Is there a scenario in which you would consider neoadjuvant radiation for rectal cancer after previous definitive radiation for prostate cancer?

Especially consider a situation where surgical excision alone is not appropriate. What if the radiation was LDR or HDR brachytherapy?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Nebraska Medical Center
Answered on

I am inclined to refrain from administering neoadjuvant radiation therapy for rectal cancer in a patient who has previously received definitive radiation therapy for prostate cancer. Instead, for these individuals, neoadjuvant chemotherapy followed by surgery appears to be a more suitable course of ...

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Mednet Member
Mednet Member
Radiation Oncology · Mayo Clinic
Answered on

Thank you Dr. @Dr. First Last for your insights. I wanted also to draw attention to a couple of older questions that also offer good discussion on this topic:

https://www.themednet.org/question/688

https://www.themednet.org/question/12095

https://www.themednet.org/question/4401

And for a more pallia...

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