Topics:
Radiation Oncology • Palliation
Is there a volume or size criteria where you feel that standard doses for palliative radiation (8Gy/1fx-30Gy/10fx) are not effective?
For example, in someone with a new diagnosis of hormone receptor positive breast cancer with a 10 cm lytic bone lesion extending out into the pelvis as a soft tissue mass, would you still utilize standard fractionation?
Answer from: Radiation Oncologist at Community Practice
At the risk of running off the mathematical rails, I thought about this question from a completely non-clinical viewpoint (from a clinical viewpoint, yes, I would probably use a bit more than 30/10 for a big 10 cm mass). Here are a few assumptions. First, the D-sub-zero (D0) for many tumor syst...
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