Is there any benefit in continuing VRd instead of VR as maintenance therapy in transplant ineligible multiple myeloma?

I love this question - mostly because it makes me think of just one study, but really, I'm excited to hear what others have to say.

I always think of RV-MM-PI-0752 (ASH 2018) studying the efficacy and feasibility of dose/schedule adjusted Rd-R vs continuous Rd in elderly and intermediate-fit newly d...

I agree. I do not see the benefit of addition of continuous dexamethasone in maintenance. Plus, one needs to be cautious about risk of infections.

Another study that looked at this was (Bringhen et al., PMID 31582542) "Lenalidomide-based induction and maintenance in elderly newly diagnosed multiple m...