Is your decision to hypofractionate or boost altered by surgeon's plans for DIEP reconstruction after radiotherapy?

I would not offer pre-operative RT off trial at this time.

If planning for lumpectomy, I would use my standard consideration (moderate hypofractionation standard, can consider 5 fx WBI for appropriately selected) and boost factors (age < 50, ER-, margins). It's unclear the rationale for a DIEP post ...