Should pituitary suppressive medications be stopped prior to radiosurgery for patients with a functioning pituitary adenoma?

The first reported significantly lower hormone normalization rate was in acromegaly patients who were receiving antisecretory medications at the time of radiosurgery. Subsequently, similar finding was reported in prolactinoma patients. The suggested rationale is antisecretory medications alter cell ...

The strongest "evidence" for holding anti-secretory medication is probably for GH secreting tumors / acromegaly, though those studies are as previously mentioned retrospective. Furthermore, I feel like most (all?) of the endpoints in those retrospective studies were regarding IGH-1 normalization. Th...