Should TNF inhibitors be held in patients undergoing radiation therapy?

We do not hold TNF inhibitors when needed for patients undergoing radiation therapy.

There is no clinical data to guide an answer for this question. Preclinical data suggests that TNFa may play a role in an effective radiation response. It may also be involved in promoting radiation toxicity. In the absence of real data, my two cents:

For definitive radiation treatments, my bias wou...