What adjuvant systemic therapy would you recommend for a woman s/p ALND for a nodal recurrence of ER-/HER2+ breast cancer 1 year after completing adjuvant therapy with paclitaxel/trastuzumab for her initial disease?  

At initial diagnosis she had T1cN0 disease treated with lumpectomy and SLNB followed by 12 weeks of paclitaxel with 1 year of trastuzumab.



Answer from: Medical Oncologist at Academic Institution
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Medical Oncologist at Mayo Clinic Rochester
Agree with the above, except that I'd at least con...
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Answer from: Medical Oncologist at Community Practice
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Medical Oncologist at NYU Winthrop Hospital
T-DXd as second line therapy.
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Answer from: Medical Oncologist at Community Practice

Answer from: Medical Oncologist at Academic Institution