What adjuvant therapy would you recommend for IA G3 endometrioid endometrial adenocarcinoma with no LVSI, MMR intact, p53wt and POLEmut?
Would you offer observation for POLE mutation in the absence of published randomized controlled trials?
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In the absence of randomized trial data, do you use POLE mutation to de-escalate adjuvant treatment for early-stage endometrial cancer?
6 physicians have voted
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