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What alternative regimens would you consider to neoadjuvant TCHP in setting of national carboplatin shortage for locally advanced HER2+ breast cancer?

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Mednet Member
Mednet Member
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida

In TRAIN-2, hospitals were allowed to use split dose carboplatin AUC 3 on days 1, 8 for 9 q3wk cycles and the pCR rates and outcomes were the same as the FEC treated group. That could be an option if you are getting limited carbo resupply on a regular basis. WSG ADAPT THP looked good for ER-HER2+ di...

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What alternative regimens would you consider to neoadjuvant TCHP in setting of national carboplatin shortage for locally advanced HER2+ breast cancer? | Mednet