Topics:
Lung Cancer • Radiation Oncology • Thoracic Malignancies • Medical Oncology • Thoracic Surgery • Non-small cell lung cancer
What are the clear criteria for unresectability in locally advanced NSCLC patients, other than medical or anatomic?
Medical inoperability is clearly defined, anatomical resectability is also pretty much clear (invasion of trachea/carina/esophagus, etc). But what about "oncological-meaningful" resectability? Bulky N2? Multi-Level N2? Many of these tumors are "technically" resectable, yet have a bad prognosis, so that we often opt for concurrent chemo-RT + durvalumab. Does a clearly defined list of such criteria exist?
Answer from: at Academic Institution
Unfortunately there is not a clearly defined criteria to answer your question. As you stated much of the debate is centered around what is "resectable N2" disease. Since there is no clear definition of what surgically resectable N2 disease much of these treatment decisions are dependent on individua...
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