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What are your management strategies for malignant pericardial effusion with a high risk of spontaneous hemorrhage, particularly in patients requiring anticoagulation for chronic atrial fibrillation?

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What are your management strategies for malignant pericardial effusion with a high risk of spontaneous hemorrhage, particularly in patients requiring anticoagulation for chronic atrial fibrillation?

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1 Answer
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Cardiology · Memorial Sloan Kettering Cancer Center
Answered on

We have many patients with malignant pericardial effusion who tolerate anticoagulation for DVT/PE/afib. In those patients, when AC is restarted (for example after pericardiocentesis), close monitoring with serial echo in a few days would be performed to see if effusion reaccumulates faster. Also, the pendulum seems to have swung back in thoracic surgery toward performing pericardial sclerosis in patients with recurrent malignant pericardial effusion. (A few years ago, they were not being done as...

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