What characteristics make a PMR patient a good candidate for sarilumab?

As rheumatologists, we are familiar with sarilumab, so we may already be comfortable using this medication. It has a role to play in managing patients with some of the following issues:

• Those who are struggling with early steroid tapers, i.e., not successfully tapering from 10 down to 5 mg/qd.
• Pati...

Patients at high risk for glucocorticoid toxicity based on co-morbidities are especially appealing candidates for sarilumab. Likewise, I think patients with a history of multiple relapses as well as those with the inability to taper less than 7.5mg of prednisone daily without recurrent signs/symptom...

In patients with Polymyalgia Rheumatica if it is hard to taper their steroid use, I would add Sarilumab as a fracture in the vertebra is pain for life.