What clinical and pathological factors guide your decision making when considering whether to recommend vaginal cuff brachytherapy following TAH/BSO for a FIGO stage IA or IB endometrial carcinoma?

The most important risk factors for vaginal wall recurrence for endometrioid adenocarcinomas are grade, depth of invasion and presence of lymphovascular invasion. Now that stage IA includes endometrium only and up to 50% myometrial invasion, it is important to consider the other risk factors. I usua...

Overall, I agree with @Dr. First Last's comments. I would add that when deciding on therapy I also use age - with older being at higher risk.