What cumulative dose constraints would you use for the normal liver when repeating SBRT for liver metastases with a longer time interval (i.e. 2-3 years)?

Topics: Radiation Oncology • Gastrointestinal Cancers • Stereotactic Body Radiotherapy • Re-irradiation

Do you factor in the time interval when deciding cumulative dose constraints?

Answer from: Radiation Oncologist at Academic Institution

I will assess cumulative dose within the normal liver with retreatment but if the interval is 2-3 years, I think there has been enough repair in a non cirrhotic liver that one could consider it nearly de novo treatment. There has been very little literature directly examining the impact of re-irradi...

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Radiation Oncologist at Radiation Oncology Associates
Dr. @Owen, thank you for such a concise and inform...

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