What dose-fractionation would you recommend using for a locally advanced, ulcerated squamous cell carcinoma resulting in a non-healing wound in the setting of multiple prior surgeries, flap reconstruction, and baseline immunosuppression?

Is there a possibility the wound could heal after radiation therapy under such circumstances?

Answer from: Radiation Oncologist at Academic Institution

I have encountered a few similar cases of ulcerated tumors, mostly advanced skin cancers. If non-resectable, full-dose standard chemo-RT; if successful in eradicating the tumor, will result in healing of the wound over time.

Answer from: Radiation Oncologist at Academic Institution

My enthusiasm for irradiating the patient would be in the low zeros. If backed into the unsavory position of treating, I’d give 70 Gy/35 fractions.

Please select the option that best describes you:

What dose-fractionation would you recommend using for a locally advanced, ulcerated squamous cell carcinoma resulting in a non-healing wound in the setting of multiple prior surgeries, flap reconstruction, and baseline immunosuppression?

Related Questions